3-D Histology Lab
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  • Islet graft histology

3-D labeling & microscopy of pancreatic islet

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Article:  3-D optical method for visualization of mouse islet microstructure and vasculature  (2010 JBO)

Article:  Mouse islet sympathetic innervation & its remodelling in injury  (2012 Diabetologia)

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Commentary:  “Islet nerves in focus – defining their neurobiological and clinical role"   (2012 Diabetologia)

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Article:  Plasticity of Schwann cells and pericytes in response to islet injury  (2013 Diabetologia)

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Article:  Imaging of islet neural network  (2014 Diabetes, Obesity and Metabolism)
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Article:  3-D imaging of islets in obesity  (2016 IJO)
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Article:  PanIN-associated pericyte, glial, and islet remodeling in 3D  (2016 AJP-GI)
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Article: Pancreatic neuro-insular network in young mice revealed by 3-D panoramic histology  (2018 Diabetologia)
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Review:  Role of accessory cells in islet homeostasis  (2018 Current Diabetes Reports)

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Article:  Lymphatic vessel remodeling and invasion in pancreatic cancer progression  (2019 EBioMedicine - The Lancet)
Review:  Pancreas optical clearing and 3-D microscopy in health and diabetes  (2021 Frontiers in Endocrinology)
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NOD mouse islets with insulitis (image and video demonstration)
Edited by Sandy Lai